Daily sildenafil dose

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Sildenafil’s short half-life necessitates multiple daily dosing schedules and the currently approved dose of 20 mg 3 times daily may be inadequate for some patients. Tadalafil has a longer half-life than sildenafil, thus allowing once-daily dosing.

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Many patients have used sildenafil daily for years with no apparent ill effects. A single case report cannot testify to the safety of regular, ultra-high doses of sildenafil; this experience must be tempered by the data on the use of sildenafil in high doses and sildenafil overdose. ERG evaluation of daily, high-dose sildenafil usage. Doc

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