Naproxen vs ibuprofen for arthritis

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Ibuprofen vs. Naproxen: Which Is More Effective for Arthritis? Both naproxen and ibuprofen are effective at reducing pain. They are more effective than Tylenol (acetaminophen), which is not an NSAID. Naproxen and ibuprofen are given as first-line (initial) therapies for many types of arthritis.

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