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exercise were randomised to semaglutide 3 mg, semaglutide 7 mg, semaglutide 14 mg or placebo once achieved a weight loss of ≥ 10% with semaglutide
mg, 10 mg or 15 mg or semaglutide 1 mg. The primary objective of SURPASS-2 was to demonstrate that the two higher doses of tirzepatide (10 mg
versus Semaglutide 1 mg in Adult Patients with Type 2 Diabetes Mellitus Added to Metformin. Semaglutide 1 mg, MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg.
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Non-inferiority to semaglutide s.c. QW was demonstrated for the doses of oral semaglutide ≥10 mg. Dose-dependent increases in adverse events (
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The drug under review is semaglutide (Rybelsus), available as an oral tablet at 3 dosage strengths: 3 mg, 7 mg, and 14 mg.10 Semaglutide is a selective GLP
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