The oral bioavailability of acyclovir is % but decreases with increasing doses. 11 Acyclovir ointment is 0.02-9.4% absorbed. 12 Acyclovir buccal tablets and ophthalmic ointment are minimally absorbed. 14,15 The bioavailability of acyclovir is not affected by food. 11. Acyclovir has a mean T max of 1.1 0.4 hours, mean C max of 593.
[max per dose: 1000 mg (3000 mg/day)] Oral/ng tube acyclovir 20 mg/kg/dose four times a day; [max per dose: 800 mg (3200 mg/day)] Zoster infection in an immunocompetent host Oral/ng tube valacyclovir 20 mg/kg/dose three times a day; [max per dose: 1000 mg (3000 mg/day)] Oral/ng tube acyclovir 20 mg/kg/dose five times a day; [max per dose: 800
There was a less than dose-proportional increase in acyclovir maximum concentration (C max) and area under the acyclovir concentration-time curve (AUC) after single-dose and multiple-dose administration (4 times daily) of valacyclovir tablets from doses between 250 mg to 1 gram.
The pharmacokinetics of acyclovir after a single dose of valacyclovir hydrochloride (1 gram) were unchanged by coadministration of a single dose of antacids (Al. 3 or Mg ). Cimetidine: Acyclovir C. max. and AUC following a single dose of valacyclovir hydrochloride (1 gram) increased by 8% and 32%, respectively, after a single dose of
Aciclovir (Acyclovir). Drug Class: Antivirals Max, Solpadeine Plus, Ultramol, Veganin, Peyona Max, Solpadeine Migraine, Solpadeine Plus
There was a less than dose-proportional increase in acyclovir maximum concentration (C max) and area under the acyclovir concentration-time curve (AUC) after single-dose and multiple-dose administration (4 times daily) of valacyclovir from doses between 250 mg to 1 gram.
Herpes simplex, orolabial disease (non-neonatal) in immuno-competent hosts, Herpes simplex virus. Acyclovir 20 mg/kg/dose (max 800 mg/dose) enterally tid. OR.
There was a less than dose-proportional increase in acyclovir maximum concentration (C max) and area under the acyclovir concentration-time curve (AUC) after single-dose and multiple-dose administration (4 times daily) of valacyclovir hydrochloride from doses between 250 mg to 1 gram.
There was a less than dose-proportional increase in acyclovir maximum concentration (C max) and area under the acyclovir concentration-time curve (AUC) after single-dose and multiple-dose administration (4 times daily) of valacyclovir tablets from doses between 250 mg to 1 gram.
Comments