Methadone routes of administration

Methadone is a strong opioid analgesic that has been used successfully in cancer pain management. The oral route of administration is generally preferred for opioid analgesics. However that route sometimes cannot be used. Experience with continuous subcutaneous methadone infusions has produced local

Rectal administration of methadone may be an alternative to intravenous and oral dosing in cancer pain, but the bioavailability of the rectal route is not known. The aim of this study was to compare the absolute rectal bioavailability of methadone with

Methadone Hydrochloride Injection is intended for parenteral (intravenous, subcutaneous and intramuscular) administration. Methadone pharmacokinetics following subcutaneous and intramuscular administration have not been systematically studied and differences among the various parenteral routes have not been well characterized.

The intensity of opium's euphoric effects on the brain depends on the dose and route of administration. Morphine, codeine, heroin, methadone, hydroquinone.

Drug Administration Routes Drug Administration Routes Administration, Inhalation Administration, Intravenous Administration, Oral Administration

Whether to divide the dose of methadone Route of administration - Management based on pain severity - Adding other opioids only as

methadone route were minimal. Subcutaneous intermittent administration of methadone appears to be a useful alternative to oral administration in selected

It is absorbed well from all routes of administration, with 80% oral bioavailability (range %). dose, calculate the initial dose of methadone using the.

Outline - Continue methadone Whether to divide the dose of methadone Route of administration - Management based on pain severity - Adding