Ciprofloxacin anaerobic coverage

Guidelines for intra-abdominal and gynecological infections recommend anaerobic coverage with a single agent. Adding metronidazole for anaerobic coverage to

ANTIBACTERIALS 1. Ciprofloxacin (PO and IV) Spectrum: best gram negative coverage of FQs, but virtually no gram positive coverage. Lacks good anaerobic

Enterococcus: Ciprofloxacin has reasonable coverage for Enterococcus faecalis, but often misses Enterococcus faecium. Anaerobic coverage: Only moxifloxacin has anaerobic coverage. However, resistance may be increasing among Bacteroides fragilis. Fluoroquinolones cover certain respiratory pathogens, including: Haemophilus influenzae.

Moxifloxacinhas some anaerobic coverage while levofloxacin and ciprofloxacin do not. Metronidazole – no longer the 1st choice for C.diff

Patients with infections resistant or likely to be resistant to other therapies. Ciprofloxacin. CIPRO, g Essentially no anaerobic coverage. Useful in:

Enterococcus: Ciprofloxacin has reasonable coverage for Enterococcus Anaerobes: Similar anaerobic coverage as compared to penicillin-G.

coverage of anaerobes. Therefore, until it is known that extended anaerobic coverage is not important for treatment of acute PID, the addition of

ciprofloxacin), and anaerobic coverage (clindamycin or metronidazole). Dual antibiotic therapy is recommended for all necrotizing soft

Ciprofloxacin (prototypical drug); Ofloxacin. 3rd generation: Levofloxacin Pyogenic Liver Abscess for anaerobic coverage); Peritonitis