Citrate lock

One newly developed locking solution has reduced the ethanol concentration in the locking solution to 20% in combination with 0.01% glyceryl trinitrate and 7% citrate. This lock showed promising results in eradicating biofilm in an in vitro test .

Citrate Toxicity (Lock) Upon entering the body, citrate is able to diffuse beyond the intravascular space and distribute throughout the total extracellular fluid.

The Citrate lock is based on tri-sodium citrate and can be safely used in all catheters! Citra-Lock 5ml vials 4% 30% -46,7%; Citra-Lock S 2 x 2,5 ml (prefilled syringe) 4% Citra-Lock S prefilled syringe. Citra-Lock 4% Twin-Pack, 2 x 2,5 ml in 5 ml syringe. Art.nr.

Whether citrate lock is more effective than saline solution or heparin lock in intensive care unit (ICU) settings and whether it is associated with a lower incidence of CRBSI remain unclear . We hypothesized that the risk of dialysis catheter infection would be lower with the use of sodium citrate locks in the ICU.

The lock solutions that were studied in this analysis were taurolidine-based lock solutions (consisting of taurolidine combined with citrate 4% and/or 500 U heparin/ml), high-concentrated citrate lock solutions (46.7%) and low-concentrated citrate lock solutions (with either 4% or 30% citrate lock solutions).

An antimicrobial-containing citrate lock is better than a heparin lock in the prevention of catheter-related infection, while citrate alone fails to show a similar advantage. Citrate locks of low to moderate concentrations, rather than high concentration, were superior to heparin locks in preventing CRBSI.

by DA Pierce 2024 Cited by 28trisodium citrate (also known as sodium citrate or citrate) has recently been shown to be an efficacious alternative to heparin as a locking solution.

BACKGROUND: Citrate solution has been suggested as an effective and safe catheter lock in hemodialysis. However, whether a citrate lock is superior to a heparin lock in preventing catheter-related infections and maintaining catheter patency is inconclusive.

Citra-Lock is a pure citrate lock solution and the best alternative for heparin catheter lock. Improves catheter patency as in many published clinical trials. Catheter lock solution, anti-clotting and antimicrobial is one of the innovations from Dirinco. Citra-Lock is recommended in the European Renal Best Practice Guidelines (ERBP) and the American Society of Diagnostic and