Omeprazole, a moderate CYP2C19 inhibitor, reduces the pharmacological activity of Plavix. Avoid using omeprazole concomitantly or 12 hours apart with Plavix. Consider using another acid-reducing agent with less CYP2C19 inhibitory activity Plavix Prescribing Information. If possible, it is recommended to avoid taking Plavix and omeprazole together.
omeprazole or esomeprazole with Plavix. Omeprazole and esomeprazole significantly reduce the antiplatelet activity of Plavix. When
(Plavix) and its use when As such, the FDA recommends. against the concomitant use of Plavix (clopidogrel) and omeprazole because the co-administration.
The metabolism of clopidogrel can also be impaired by drugs that inhibit CYP2C19, such as omeprazole [Prilosec] or esomeprazole [Nexium]. Avoid concomitant use of Plavix with omeprazole or esomeprazole because both significantly reduce the antiplatelet activity of Plavix. Plavix Prescribing Information
Omeprazole, a moderate CYP2C19 inhibitor, reduces the pharmacological activity of Plavix. Avoid using omeprazole concomitantly or 12 hours apart with Plavix. Consider using another acid-reducing agent with less CYP2C19 inhibitory activity Plavix Prescribing Information. If possible, it is recommended to avoid taking Plavix and omeprazole together.
Plavix (clopidogrel) patients should be Leading cardiologists challenge clinical importance of interaction between clopidogrel (Plavix) and omeprazole
activity of PLAVIX than omeprazole (see DRUG INTERACTIONS and ACTION AND. CLINICAL PHARMACOLOGY). Gastrointestinal. Active GI lesions. PLAVIX
Omeprazole, a moderate CYP2C19 inhibitor, reduces the pharmacological activity of Plavix. Avoid using omeprazole concomitantly or 12 hours apart with Plavix. Consider using another acid-reducing agent with less CYP2C19 inhibitory activity Plavix Prescribing Information. If possible, it is recommended to avoid taking Plavix and omeprazole together.
(Plavix) and its use when As such, the FDA recommends. against the concomitant use of Plavix (clopidogrel) and omeprazole because the co-administration.
Hence Omeprazole being a much more expensive drug than it is now.....